After 17 years, John Isner’s career came to an end with a five-set defeat to fellow American Michael Mmoh at the US Open

Andy Murray was outclassed by Grigor Dimitrov in New York, where Jack Draper defeated an ailing Hubert Hurkacz

Novak Djokovic eased past Bernabé Zapata Miralles in New York as seventh seed Stefanos Tsitsipas suffered a shock defeat

Unhappy about playing on an outside court, Holger Rune was handed a humbling defeat in New York as Maria Sakkari also fell

Carlos Alcaraz and Jannik Sinner are on a collision course again in New York, where Iga Swiatek and Coco Gauff could also meet

Coco Gauff will be among the favourites at the US Open after a career-best title win against Karolina Muchova in Cincinnati